High-end In-situ Ionization Mass Spectrometry Cooperative Lab Listed at Peking University

[China Instrument Network Instrument Development] In order to accelerate the tremendous changes in the analytical and inspection industry, it explores and develops advanced technologies that are fast, green, in-situ, and real-time analysis and detection. Recently, the "PKUAIC-ASPEC AIMS Joint Lab" jointly established by the Analytical Testing Center of Peking University and the Chinese company Tyco was established.

It is reported that the Analytical Test Center of Peking University was established in 1983. It is the first analytical test institution that has passed national metrology certification and can issue authoritative test reports. It is an important analytical test platform for Peking University and even the testing industry. Tyco is one of the earliest enterprises to promote the in situ ionization mass spectrometry technology in China. It undertakes major national mass spectrometry projects such as the 12 863 Science and Technology, and has reached more than 20 collaborative research projects with national research institutes. Special application projects were initiated and jointly organized with the China Mass Spectrometry Society to host the China In-Situ Ionization Mass Spectrometry Conference and gained extensive international acclaim. Products include real-time direct analysis ion source (DART), analytical electrospray ionization (DESI), multichannel nanospray ionization source (TVNM), atmospheric matrix-assisted laser desorption ionization (AP-MALDI), ultrahigh molecular weight MALDI mass spectrometer detectors (HM4, Pearl) and so on. The two parties jointly explore and develop the in-situ detection core, assist the collaborative development of production, learning and research, and promote the development of the in-situ ionization technology in the analytical technology field. The in-situ ionization mass spectrometry application and development joint laboratory relies on the leading platform of Peking University Analysis and Testing Center and the advanced detection technology equipment of Hydatology China to accelerate the development of in situ ionization basic theoretical research and industrialization, and further promote domestic in-situ ionization mass spectrometry and In-situ inspection of the industry's development, the development of advanced fast screening, identification, quantitative analysis technology, should be green, fast, convenient, and just in-situ detection. The two sides are committed to promoting deep technological changes in key applications of in-situ ionization technology, breaking through old analytical standards or technological bottlenecks.

Prof. Zhang Xinxiang, Deputy Director of Analytical Testing Center of Peking University; Professor Xie Jinglin, Deputy Director of Analytical Testing Center of Peking University; Professor Zhou Jiang, Analytical Testing Center of Peking University; Zhou Wen, Analytical Testing Center of Peking University; Brian Musselman, President of IonSence, USA Mr. Liu Chunsheng, President and Chief Executive Officer of Shinetech, Tommy Tang, Chief Operating Officer of China Amateur Tyco, Mr. Jia Wanyin, Marketing Manager of China Quality Tyco, and Mr. Duan Xiaoyi, Manager of Technical Department of China Tyco, and Professor Li Hongmei, Director of Chemistry Measurement and Analysis Institute, China Jiliang University. Professor Liao Jie, director of the Experimental Center of the General Hospital of the Chinese People's Liberation Army, and associate professor Li Qin of the Peking University Medical College attended the listing ceremony.

Fast, accurate and highly sensitive are the criteria for perfection of detection technology. The development of in-situ ionization mass spectrometry technology leads the new trend of real-time detection technology. Its penetration in various industries has profoundly affected the frontiers of organic analysis. The iKnife and the MassSpec Pen are just some of the successful applications in this field.

The in-situ mass spectrometry (AIMS) technology is the latest mass spectrometry technology to meet the needs of fast, on-site, direct, non-destructive, high-throughput, high-sensitivity, and highly-specific analysis. This kind of technology has a unique sample desorption, ionization, and separation of the injection mechanism, without or only requires very simple sample preparation, in food, medicine, materials, physical evidence, environmental and other areas of security testing and quality control, in Group analysis, new drug development, Chinese medicine and natural product analysis, imaging, precision medicine, and health have been widely used. In the past five years, Stanford, MIT, Harvard, Cambridge, Peking University, National Taiwan University, Zhongda University, Fudan University, National University of China, Zhejiang University, Pharmaceutical University, Mine University and other famous universities at home and abroad, the United States NIH, EPA, NIST, Chinese Academy of Sciences, Chinese Academy of Medical Sciences, Agricultural Science Institutes, Institutes of Science and Technology, Institute of Metrology and Authoritative Scientific Research Institutes, Roche, Merck, Pfizer, Nestle and other multinational companies, FDA, FBI, Ministry of Public Security, Quality Inspection Bureau, Entry-Exit, Drug Administration and other law enforcement agencies have adopted such technologies and equipment.

With the accelerating pace of life and people’s attention to issues such as environmental quality and food safety, traditional analytical methods have become more and more popular in the analysis and detection of complex samples or a large number of samples such as foods, pharmaceuticals, biological products, agricultural products, and materials. Many disadvantages. Complex sample bases, cumbersome sample preprocessing, complex experimental design, variable data analysis, and many uncertain human factors have become bottlenecks, limiting the efficiency of analysis and limiting the speed of analysis. The in-situ ionization mass spectrometry technology can efficiently and sensitively analyze various complex samples directly. It is a major change in mass spectrometry, and it has rapidly penetrated in various industries, leading to the development and application of a new generation of analytical detection technology. It has been widely and typically used in environmental chemistry, food safety, legal testing, explosives and drug analysis, mass spectrometry imaging, drug analysis, packaging materials, synthetic polymer compound analysis, biological analysis, and precision medicine. For example: food, beverages, agricultural products and aquatic products safety inspections; drug safety testing and counterfeiting and control; drug development, analysis and identification of traditional Chinese medicines and natural products; judicial physicochemical testing and anti-counterfeiting identification; toxic components of packaging materials, plastics and textile products; Organic compounds on the surface of concrete, glass, etc.; monitoring of contaminants such as production lines and on-site reactions; molecular imaging of tissue sections; clinical examination of tumor screenings; analysis of protein lipids; contamination investigation of liquid crystal devices; adulteration screening of health products; environmental toxin pesticides Fast screening, etc., a wide range of applications.

Zhang Xinxiang, deputy director of the Analytical and Testing Center of Peking University, said that the Beijing University’s analysis and testing center has the highest research and development capabilities in the country and will make full use of the platform to cooperate with various companies to develop new technologies and promote the development of scientific research and commerce.

Regarding the industry impact of the joint laboratories, Zhou Jiang, head of the mass spectrometry platform of the Analytical Test Center of Peking University, said that the joint laboratory set up by the Analytical Test Center of Peking University and Huatech Tyco can help more researchers understand the in situ ionization mass spectrometry. It also helps to promote the development of rapid detection techniques for some conventional samples, such as food samples. For the in-situ ionization mass spectrometry industry, more research, including the study of specific samples on large scientific research platforms, can help improve the software and hardware design of in-situ ionization mass spectrometry, and can promote research platforms and product development companies. Develop together.

Liu Chunsheng, President and Chief Executive Officer of HTI, said: The joint laboratory for in situ ionization mass spectrometry application and development will be dedicated to solving the problem of miniaturization, portability, practicalization, and procedural practical technologies for in situ ionization mass spectrometry, so that on-site personnel can rely on it. The program flow can be easily managed and used.

(Original title: High-end in-situ ionization mass spectrometry laboratory was listed at Peking University)